Detail
Product Name: Acetaminophen; Also known as paracetamol
Chinese chemical name: 4-hydroxyacetanilide; N - (4-hydroxyphenyl) acetamide
English chemical name: 4-hydroxycetanilide; 4-AcetaminoPhenol
Molecular formula: C8H9NO2
Structural type:
Molecular weight: 151.16
CAS No.: 103-90-2
Properties: white crystal or crystalline powder; Odorless and slightly bitter. Melting point 168 ~ 172 ℃. It is soluble in hot water or ethanol, soluble in acetone and slightly soluble in water.
Function and purpose:
For the preparation of acetaminophen.
This product belongs to antipyretic and analgesic drugs. It can inhibit the synthesis of prostaglandins and has antipyretic and analgesic effects.
It is used for fever caused by common cold or influenza, and also for relieving mild to moderate pain such as headache, joint pain, migraine, toothache, muscle pain, neuralgia and dysmenorrhea.
packing:
The inner two-layer high-density edible polyethylene film bag is sealed, and the outer cardboard is sealed with a rigid barrel made of adhesive.
Quality index:
Main items (according to the standard of Chinese Pharmacopoeia 2010, Part II) | index |
Identification: infrared absorption spectrum | It should be consistent with the atlas of the control (atlas 131) |
Acidity (PH) | Shall be 5.5 ~ 6.5 |
Clarity and color of ethanol solution (1.0g, dissolved in 10ml of ethanol) |
The solution shall be clear and colorless |
Chloride (2.0g, add 100ml of water to heat and dissolve the filtrate) | Should be < 0.01% |
Sulfate (2.0g, add 100ml of water to heat and dissolve the filtrate) | Shall be < 0.02% |
Related substances (high performance liquid chromatography) | The content of para aminophenol shall not exceed 0.005%; Other impurities: < 0.1%, and the total amount of impurities shall not exceed 0.5% |
P-chlorobenzene acetamide (HPLC) | Not more than 0.005% |
Loss on drying (drying to constant weight at 105 ℃) | The weight loss shall not exceed 0.5% |
Burning residue | Not more than 0.1% |
heavy metal | Not more than 10 parts per million |
Content (UV spectrophotometry) | The content of C8H9NO2 shall be 98.0% ~ 102.0% |
In addition to the above standards, we can also supply products according to national standards according to customer requirements.
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